Engineered Biomaterials to Enhance Stem Cell-Based Cardiac Tissue Engineering and Therapy
نویسندگان
چکیده
منابع مشابه
Role of Stem Cells in Cardiac Cell Therapy and Tissue Engineering
Background: In spite of promising results of conventional treatments for myocardial infarction, including medications, stent implantation, and coronary artery bypass grafting, the disease and its complications, especially heart failure, are highly prevalent because these methods could not reverse the cell loss, which is the main problem. Currently, heart transplantation, as the last option f...
متن کاملStem cell-based tissue engineering with silk biomaterials.
Silks are naturally occurring polymers that have been used clinically as sutures for centuries. When naturally extruded from insects or worms, silk is composed of a filament core protein, termed fibroin, and a glue-like coating consisting of sericin proteins. In recent years, silk fibroin has been increasingly studied for new biomedical applications due to the biocompatibility, slow degradabili...
متن کاملBiomaterials for Cardiac Tissue Engineering
Cardiovascular diseases (CVD) are a leading death cause in developed countries (1 of every 3 deaths in the United States in 2008) [1]. Changes in diet and habits are causing CVD to become major mortality pathologies in developing countries too [2] (they are already responsible for a 30% of the world deaths). This group of diseases constitutes a great burden for the national health systems, cons...
متن کاملCardiac tissue engineering and regeneration using cell-based therapy
Stem cell therapy and tissue engineering represent a forefront of current research in the treatment of heart disease. With these technologies, advancements are being made into therapies for acute ischemic myocardial injury and chronic, otherwise nonreversible, myocardial failure. The current clinical management of cardiac ischemia deals with reestablishing perfusion to the heart but not dealing...
متن کاملTissue Engineering and Regenerative Medicine Stem Cell-Based Tissue-Engineered Laryngeal Replacement
Patientswith laryngeal disordersmay have severemorbidity relating to swallowing, vocalization, and respiratory function, forwhich conventional therapies are suboptimal. A tissue-engineered approach would aim to restore the vocal folds and maintain respiratory function while limiting the extent of scarring in the regenerated tissue. Under Good Laboratory Practice conditions, we decellularized po...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Macromolecular Bioscience
سال: 2016
ISSN: 1616-5187
DOI: 10.1002/mabi.201500396